is a rare genetic disorder linked to diabetes. Wolfram Syndrome is so rare it impacts only 1 in 700,000 people. Symptoms include vision and hearing loss and life-threatening respiratory problems. Wolfram Syndrome is inherited as an autosomal recessive condition. Both parents carry one abnormal copy of the Wolfram gene, and one normal copy. For a child to be affected, he has to inherit two abnormal copies, one from each parent.
There is no known treatment for Wolfram Syndrome beyond managing the resulting complications. Life expectancy of the average person suffering from this syndrome is about 30 years.